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KMID : 0355219850090010011
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Journal of Korean Academy Oral Medicine
1985 Volume.9 No. 1 p.11 ~ p.22
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HISTOPATHOLOGICIAL STUDY ON TEETH, JAWBONE, AND ORAL TISSUES IN POISONED RABBIT.
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Abstract
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The authors administered KCN, NaF, As=O, orally to rabbits and caused acute and chronic poisoning, then studied the teeth, jaw bones, and other oral tissues histopathologically and histochemically.
The results were as follows,
1. There was no significant difference between acute poisoned group by NaF and control group. But, vasodilatation in the connective tissues, especially marginal area of jaw bone, atrophy and destruction of glandular cells was observed.
2. Chronic poisoned group by NaF showed degeneration and thickening of subeutanec"active´. tissues, atrophy and degeneration of subcutaneous connective tissues, atrophy and degeneration of muscle fibers, vasodilatation and hyperemia, fat- acEuniilation in bone cavities (lacunae). and degeneration n of odontoblas s in pulp tissue.
3. Acute poisoned group by RCN showed almost moil appearances a control group, and chronic po d SAP showed hyperplasia of Nasal layer in epithdanm, degenerstiour of subcutaneous connective tuns. vasodil-atation and hyperemia, severe hemorrhage of marginal area of jaw bone, hype rplada of salivary gland ducts, but normal arrangement of muscle fibers and narrow bone rarity (lacunae) due to active osteoblastic action, osteodentin were observed.
4. Acute poisoned group by As2O3 showed degeneration of basal cell, atrophy of blood vessels in palatal muscosa. Chronic poisoned group showed irregular cell arrangement and degeneration, reduction of capillaries in palatal mucosa. Osteoclasts in jaw bone were observed.
5. In Mason´s Trichrome and Van Gieson Staining, chronic poisoned group by NaP hawed thickening and loosening of subcutaneous connective tissues. Hyperplasia of intermuscular connective tissue was observed in chronic poisoning by RCN and NaF. In PAS staining, negative reaction in outer layer of palatahaacosa. positive reaction in keratin layer and mild reaction of basal layer in palate and tongue mucosa was observed.
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KEYWORD
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